"We have started the phase-III trials of the vaccine (candidate Covishield). We will administer dose to 150 to 200 volunteers," said Dr Muralidhar Tambe, Dean, Sassoon General Hospital.
The move comes even as India's drug regulator has extended Covishield's shelf life from six to nine months from its manufacturing date.
A source closely involved in logistical arrangements said the movement of vaccine doses is likely to start from early Tuesday morning through road and air routes amid elaborate police security.
But no extra risk after second dose, shows study led and funded by drug maker, reports Sohini Das.
The trio used the same principles of evolution -- genetic change and selection -- to develop proteins used in a range of fields.
Two men, aged 32 and 48, were given the first shot of the 'Covishield' vaccine, being manufactured by Pune-based Serum Institute of India, at Bharti Vidyapeeth's Medical College and Hospital on Wednesday. The dose will be repeated after one month, an official said.
The Central Drugs Standard Control Organisation has granted restricted emergency use authorisation to two new vaccines and a drug for COVID-19, taking the number of preventives and treatments available in India to 12.
"The phase-III trial of 'Covishield' vaccine will begin at Sassoon hospital from next week. It is likely to start on Monday. Some volunteers have already come forward for the trial. "Around 150 to 200 volunteers will be administered the vaccine candidate dose," Dean of the state-run Sassoon General Hospital Dr Muralidhar Tambe said.
Embroiled in a bruising controversy in the shadow of the #MeToo campaign, the Swedish Academy has postponed the 2018 award until next year, when it will name two winners.
All three scientists have played a leading role in the Laser Interferometer Gravitational-Wave Observatory, or Ligo, experiment, which made the first historic observation of gravitational waves in September 2015.
The DCGI arrived at the conclusion on Wednesday based on the recommendations of an independent expert committee which has also opined that compensation should not be paid to the volunteer, they said.
If there was one event that made the month of August stand out, it was a strengthening of the dollar index to levels last seen only 20 years ago, as the Federal Reserve dispelled all doubts about its intention to continue raising interest rates. Predictably, most currencies suffered against the US unit, with the bulk of the losers belonging to the emerging markets pack. Amid the volatility, the rupee, however, has displayed significant resilience and fared much better than most of its peer currencies.
Two American scientists and one from Germany have won the Nobel prize for chemistry for the development of super-resolved fluorescence microscopy.
Ever wondered why the Nobel Peace Prize is given by a Norwegian Committee in Oslo and not in the Swedish capital unlike the other Nobel awards?
Currently, phase 2 and 3 clinical trials of the Oxford vaccine candidate is going on in the United Kingdom, phase 3 clinical trial in Brazil and phase 1 and 2 clinical trials in South Africa.
As India holds its breath for the Covid vaccination to be begin, Sudhir Bisht provides a quick checklist of what you must know about the vaccines that will be administered to citizens.
The show-cause notice was issued following reports that human trials of the most promising COVID-19 vaccine candidate, being developed by the University of Oxford, have been put on hold after a United Kingdom participant had an adverse reaction to it.
The Drugs Control General of India has permitted emergency use of Covid vaccine Sputnik V with certain conditions, clearing the way for a third vaccine in addition to Covishield and Covaxin. Besides, the government on Tuesday also fast-tracked emergency approval for other jabs. Here is what the vaccines are all about:
The DCGI also directed Serum Institute of India to increase the safety monitoring of the subjects already vaccinated as part of the trial, and submit the plan and report.
'The political environment makes it extremely difficult for youngsters to be hopeful about their lives, and focus on their dreams.'
The prime minister was apparently referring to Swedish environmentalist Greta Thunberg's controversial 'toolkit', which she tweeted and then deleted, outlining ways in which people can participate in the farmers protest.
India's import of weapon systems is three times higher than Pakistan and China as it continues to be the largest buyer of arms in the world, a Swedish think tank said on Monday.
The remarks come amid suspected cases of COVID-19 reinfection being reported from abroad and from Indian states like Telangana, Karnataka, Gujarat, Punjab and Maharashtra.
Here are the top 10 images from the big news that shook the world in the previous week.
Ohsumi, born in 1945 in Fukuoka, Japan, has been a professor at the Tokyo Institute of Technology since 2009.
As India prepares to launch its vaccine drive on January 16, here is a look at the options:
French and American scientists win Nobel Physics Prize
This year's Laureates have shown how the problem of global poverty can be tackled by breaking it down into a number of smaller - but more precise - questions at individual or group levels, he Royal Swedish Academy of Sciences said.
Banerjee, 58, was educated at the University of Calcutta, Jawaharlal Nehru University and Harvard University, where he received his Ph.D in 1988. He is currently the Ford Foundation International Professor of Economics at the Massachusetts Institute of Technology.
Y C Deveshwar, chairman, ITC, received the Award at a ceremony held at Rio.
The Nobel Prize in Chemistry 2012 was awarded jointly to Robert J. Lefkowitz and Brian K. Kobilka "for studies of G-protein-coupled receptors"
In the changed circumstances and attitudes in Britain, we must let bygones be bygones, argues Colonel Anil A Athale (retd).
Based on micro fuel cell technology developed at KTH Royal Institute of Technology in Stockholm, the MyFC PowerTrekk uses ordinary water to extend battery life for devices of up to 3 watts.
Over the years, a noticeable unpleasantness began to develop between senior and junior, Sorabjee and Salve. Salve gave credit, for his rise in the profession, to Nani Palkhivala, and not to Sorabjee. This hurt Sorabjee, though he never admitted it.
Take the Rediff Biz Quiz and find out how much you know about the Nobel Prize in Economics.
They won for their analysis of markets with search frictions.
A massive pan-India inoculation drive against COVID-19 was set in process on Tuesday with more than 56 lakh doses of the Covishield vaccine flown to 13 cities across India from Pune and taken to designated national and state-level stores amid tight security.
While China's arms imports accounted for nine per cent of the global defence sales, the same figure for India was seven per cent
Frenchman, 2 Americans win Nobel Chemistry prize
The American trio of Jeffrey C Hall, Michael Rosbash and Michael W Young won for "for their discoveries of molecular mechanisms controlling the circadian rhythm".
